Dosage and Administration Guidelines for Amantadine

Amantadine dosage depends on the specific condition being treated and the patient’s individual response. Always follow your doctor’s instructions precisely.

Parkinson’s Disease

For Parkinson’s disease, treatment typically begins with a low dose, gradually increasing as tolerated. A common starting dose is 100 mg once or twice daily. The dosage may be increased by 100 mg every 3-7 days, up to a maximum of 800 mg per day, divided into multiple doses.

Influenza A

For influenza A prophylaxis (prevention), the usual adult dose is 200 mg daily. For treatment, the typical dose is 200 mg twice daily for several days. Children’s dosages vary significantly by age and weight; consult your doctor or pharmacist for precise pediatric guidelines.

Dosage Adjustments

    Renal Impairment: Reduced dosage is often necessary for patients with kidney problems. Your doctor will adjust the dose based on your creatinine clearance. Hepatic Impairment: Dosage adjustments may be necessary for patients with liver disease. Consult your physician. Older Adults: Older adults may require lower doses due to increased sensitivity to amantadine’s effects. Starting with a lower dose and monitoring closely is recommended.

Administration

Amantadine is typically administered orally, either as an immediate-release tablet or a capsule. Take amantadine with food or milk to minimize potential gastrointestinal upset. Swallow the tablets or capsules whole; do not crush, chew, or break them. Maintain consistent dosing intervals to ensure steady blood levels of the medication.

Missed Dose

If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Never double up on doses.

Stopping Treatment

Do not stop taking amantadine suddenly without consulting your doctor. Gradual dose reduction is usually recommended to minimize potential withdrawal symptoms.

Important Note:

This information is for general knowledge and does not constitute medical advice. Always consult your doctor or pharmacist before starting, stopping, or altering the dosage of any medication, including amantadine. They can provide personalized guidance based on your specific health needs and medical history.