Amoxicillin/clavulanate (Augmentin) can interact negatively with certain medications. Always inform your doctor or pharmacist about all medications you are taking, including over-the-counter drugs, supplements, and herbal remedies.
Medications to Avoid or Use With Caution:
- Methotrexate: Amoxicillin/clavulanate can increase methotrexate levels, potentially causing serious side effects. Your doctor may need to adjust your methotrexate dose. Oral contraceptives: Amoxicillin/clavulanate may reduce the effectiveness of birth control pills. Consider using a backup method of contraception while taking this antibiotic. Warfarin (Coumadin): This antibiotic can interfere with warfarin’s ability to thin the blood, potentially increasing the risk of bleeding. Close monitoring of your INR (International Normalized Ratio) is necessary. Allopurinol: Concurrent use may increase the risk of skin reactions. Probenecid: This drug can increase amoxicillin levels, potentially leading to higher risk of side effects. Your doctor may adjust the amoxicillin dose if you’re taking probenecid.
Other Potential Interactions:
Some antibiotics may interact with specific laboratory tests. Inform your doctor you are taking amoxicillin/clavulanate to prevent inaccurate test results. Certain medications can affect how your body absorbs and processes amoxicillin/clavulanate, potentially affecting the treatment’s efficacy. Discuss this with your physician before taking any new medications. Alcohol consumption during your antibiotic treatment isn’t recommended; it may cause side effects to worsen.
This information is not exhaustive. Always consult your doctor or pharmacist for personalized advice on potential drug interactions.
