Review your medications with your doctor or pharmacist. This includes prescription drugs, over-the-counter medications, and supplements. Certain drugs can interact negatively with metformin, potentially affecting blood sugar control. For example, some diuretics and corticosteroids can increase blood glucose levels, counteracting metformin’s effects.
Common Drug Interactions
Be aware of interactions with drugs like: beta-blockers (may mask hypoglycemic symptoms), thiazide diuretics (can increase blood glucose), and some NSAIDs (nonsteroidal anti-inflammatory drugs). Your healthcare provider can help you identify potential risks based on your specific medications and health conditions. Regular blood glucose monitoring is critical during medication adjustments.
If you experience unusual blood sugar fluctuations or other side effects while taking metformin, contact your doctor immediately. Don’t hesitate to discuss any concerns regarding drug interactions. Open communication with your healthcare team is key to safe and effective treatment.


