Interactions with Other Medications and Substances

Always inform your doctor about all medications you are taking, including over-the-counter drugs, herbal supplements, and recreational drugs, before starting Sildenafil oral film. This includes nitrates (used for chest pain), alpha-blockers (used for high blood pressure or prostate problems), and certain antifungals. Combining Sildenafil with these medications can cause a dangerous drop in blood pressure.

Specific Medication Interactions

Sildenafil can interact negatively with several classes of drugs. For example, co-administration with strong CYP3A4 inhibitors (like ketoconazole or ritonavir) can increase Sildenafil levels, potentially leading to side effects. Conversely, inducers of CYP3A4 (like rifampin) may decrease Sildenafil’s effectiveness. Discuss these interactions with your physician to adjust dosages or explore alternative treatments if necessary. Avoid grapefruit juice, as it can also affect Sildenafil metabolism.

Alcohol and Other Substances

Consuming alcohol while using Sildenafil may increase the risk of side effects, including dizziness and headaches. Limit alcohol intake or avoid it completely while taking the medication. Similarly, recreational drug use may exacerbate Sildenafil’s side effects and pose health risks. Openly discuss your lifestyle choices with your doctor to assess potential risks and make informed decisions.