Mechanism of Action: How Qvar and Prednisone Work

Qvar (beclomethasone dipropionate) is an inhaled corticosteroid. It works locally in your lungs, reducing inflammation by binding to glucocorticoid receptors inside lung cells. This binding decreases the production of inflammatory substances like leukotrienes and cytokines, thus lessening swelling and mucus production. The effects are primarily localized to your airways, minimizing systemic side effects.

Qvar: Targeted Action

Remember, Qvar’s impact is focused on the lungs, making it a preferred choice for localized airway inflammation. This targeted approach reduces the risk of widespread side effects associated with systemic steroids.

Prednisone, conversely, is a systemic corticosteroid. It affects your entire body by binding to glucocorticoid receptors throughout your system. This widespread action suppresses the immune system, reducing inflammation wherever it occurs. While this is helpful for widespread inflammation, it also carries a greater risk of side effects.

Prednisone: Systemic Effects

Prednisone’s broad impact on your body contributes to its effectiveness against severe inflammation but increases chances of side effects like weight gain, high blood sugar, and mood changes. Doctors usually prescribe it for short durations to minimize these risks.

In short: Qvar provides localized relief for airway inflammation, while prednisone offers systemic relief for widespread inflammation, but with a higher risk profile.