Naproxen, while effective, can cause side effects. Common ones include stomach upset, heartburn, and nausea. These are often mild and may resolve with food or antacids. However, more serious side effects are possible, though less frequent.
Gastrointestinal Issues
Naproxen can irritate the stomach lining, leading to ulcers or bleeding. If you experience severe stomach pain, bloody or black stools, or vomit that resembles coffee grounds, seek immediate medical attention. Prior history of ulcers or gastrointestinal bleeding increases this risk. Consider taking naproxen with food or milk to mitigate stomach upset.
Cardiovascular Concerns
Increased risk of heart attack or stroke is associated with long-term or high-dose naproxen use. Individuals with pre-existing heart conditions or risk factors (such as high blood pressure, high cholesterol, or smoking) should discuss naproxen use with their doctor before starting treatment. Regular monitoring of blood pressure and cholesterol is advisable.
Kidney Problems
Naproxen can sometimes affect kidney function, particularly in individuals with pre-existing kidney disease or dehydration. Drink plenty of fluids while taking naproxen. Report any signs of kidney problems, like swelling in your legs or ankles, decreased urine output, or changes in urination frequency, to your healthcare provider immediately.
Allergic Reactions
Although uncommon, allergic reactions can occur. Symptoms include rash, itching, swelling, and difficulty breathing. If you experience an allergic reaction, stop taking naproxen and seek immediate medical help.
Interactions
Naproxen can interact with other medications, including blood thinners, certain diuretics, and some antidepressants. Always inform your doctor and pharmacist of all medications and supplements you are taking before starting naproxen.
Pregnancy and Breastfeeding
Pregnant or breastfeeding women should consult their doctor before using naproxen. The risks and benefits need careful consideration for this population. Naproxen can potentially affect the fetus or infant.


