Understanding Viagra’s Mechanism of Action

Viagra, or sildenafil, works by inhibiting an enzyme called phosphodiesterase-5 (PDE5). PDE5 breaks down a molecule called cyclic guanosine monophosphate (cGMP). High cGMP levels relax blood vessels, leading to increased blood flow.

How This Affects Erections

During sexual stimulation, nitric oxide is released, increasing cGMP levels. By blocking PDE5, Viagra prolongs the effects of cGMP. This sustained increase in cGMP causes the smooth muscles in the penis to relax, allowing more blood to flow into the corpora cavernosa–the spongy tissue responsible for erections. This increased blood flow results in a firm erection.

Important Considerations

Viagra’s effect relies on existing sexual stimulation; it doesn’t spontaneously create an erection. Remember to consult a doctor before using Viagra, especially if you have underlying health conditions, such as heart problems or high blood pressure. They can assess your suitability for the medication and provide appropriate guidance.