Pronounce zidovudine as Zy-DOE-vyou-deen. The emphasis falls on the second syllable, “DOE”.
Breaking it down further helps: “zy” sounds like the beginning of “zip,” “DOE” is like the word “doe,” “vyou” rhymes with “few,” and “deen” concludes with a soft “n” sound as in “seen”. Practice each syllable individually before combining them for a smooth pronunciation.
Remember to pay close attention to the soft “v” sound in “vyou” to avoid mispronunciation. Consistent practice will build your confidence and accuracy.


