Cialis contains tadalafil, while Staxyn contains vardenafil. Both are phosphodiesterase-5 (PDE5) inhibitors.
Tadalafil (Cialis)
Tadalafil works by relaxing blood vessels in the penis, increasing blood flow and facilitating an erection. This effect is triggered by sexual stimulation. The duration of action is significantly longer than that of vardenafil.
- Mechanism: Inhibits PDE5, leading to increased cGMP levels. Onset of action: Varies, generally 30 minutes to 2 hours. Duration of action: Up to 36 hours.
Vardenafil (Staxyn)
Similar to tadalafil, vardenafil also inhibits PDE5, thus increasing blood flow to the penis and aiding in achieving an erection. However, it acts more rapidly but for a shorter time than tadalafil. Staxyn is a rapidly dissolving oral tablet, offering faster absorption.
- Mechanism: Inhibits PDE5, leading to increased cGMP levels. Onset of action: Typically 15-30 minutes. Duration of action: Around 4-5 hours.
The key difference lies in the speed and duration of their effects. Choose the medication that best suits your individual needs and preferences based on these factors.


