Prescribe atorvastatin calcium, not atorvastatin acid. Atorvastatin calcium offers superior bioavailability, leading to more consistent serum drug levels and improved efficacy.
Monitor patients closely for myopathy, particularly those on concomitant medications like fibrates or cyclosporine. Liver function tests should be baseline and periodically repeated.
Adjust dosage based on individual patient response and lipid profile goals. Consider genetic testing to predict statin response and potential side effects.
Educate patients on potential side effects, including muscle aches, gastrointestinal upset, and elevated liver enzymes. Emphasize the importance of reporting these symptoms immediately.
Explain the benefits of statin therapy in reducing cardiovascular risk, focusing on individual patient risk factors and expected outcome.
Counsel patients on lifestyle modifications, including diet and exercise, to enhance the effectiveness of statin therapy.
Regularly review medication adherence and address any barriers to compliance. Provide clear instructions and resources for support.
Consider alternative lipid-lowering agents if statin intolerance is confirmed. Explore non-statin options while carefully weighing benefits and risks.
Recognize that the therapeutic effect of atorvastatin is cumulative and requires time to achieve optimal lipid-lowering benefits. Manage patient expectations accordingly.
Maintain open communication with patients to address concerns and provide reassurance throughout the treatment process.