Untreated or inadequately treated amoxicillin-resistant strep pharyngitis can lead to several serious complications. Rheumatic fever, a severe inflammatory condition affecting the heart, joints, brain, and skin, is a major concern. It arises from the body’s immune response to the infection, potentially causing permanent heart damage (rheumatic heart disease) requiring ongoing medical management, including medication and potentially surgery. Early diagnosis and appropriate antibiotic treatment are crucial to prevent this.
Cardiac Complications
Rheumatic heart disease, a consequence of rheumatic fever, can manifest as valvular heart disease, requiring regular monitoring and intervention. This may involve lifestyle adjustments and medication to manage symptoms and prevent further complications. In severe cases, valve replacement surgery might be necessary.
Glomerulonephritis
Another potential complication is post-streptococcal glomerulonephritis, an inflammatory kidney disorder. Symptoms include swelling, high blood pressure, and changes in urine output. While most cases resolve with supportive care, some may lead to chronic kidney disease, requiring long-term monitoring and potentially dialysis or transplantation. Early detection and management are key to optimizing outcomes.
Prognosis
The prognosis for amoxicillin-resistant strep pharyngitis is generally good with appropriate antibiotic treatment. Identification of the resistant strain through culture and sensitivity testing is vital for guiding treatment decisions. A suitable alternative antibiotic regimen should be promptly implemented. However, the potential for long-term cardiac and renal issues highlights the importance of early diagnosis and effective treatment to minimize these risks. Regular follow-up appointments are recommended to monitor for any complications.
