Donepezil is a cholinesterase inhibitor. It works by increasing levels of acetylcholine, a neurotransmitter crucial for memory and thinking. This increased acetylcholine helps improve cognitive function in individuals with Alzheimer’s disease.
How Donepezil Affects the Brain
Acetylcholine is broken down by an enzyme called acetylcholinesterase. Donepezil blocks this enzyme, slowing down the breakdown of acetylcholine and allowing it to remain active longer in the brain’s synapses. This prolonged activity improves communication between brain cells.
Dosage and Administration
Donepezil is available in various strengths and is usually taken orally once daily, at bedtime. Your doctor will determine the appropriate dosage based on your individual needs and response to treatment. Always follow your doctor’s instructions precisely.
Potential Side Effects
Common side effects include nausea, vomiting, diarrhea, and insomnia. Less frequent but more serious side effects can occur; you should report any unusual symptoms to your doctor immediately. They will discuss the benefits and risks of treatment with you.
