Avoid azithromycin if you have a known allergy to azithromycin, erythromycin, or any other macrolide antibiotic. This includes severe allergic reactions like anaphylaxis.
Liver Issues
Azithromycin can cause liver damage. Therefore, individuals with pre-existing liver disease should use caution. Your doctor will carefully assess your liver function before prescribing.
- Consult your physician if you experience jaundice, dark urine, or clay-colored stools. Regular liver function tests may be necessary during treatment.
QT Prolongation
Azithromycin can prolong the QT interval on an electrocardiogram (ECG). This poses a risk of serious heart rhythm disturbances, especially in patients with underlying heart conditions or those taking other medications that prolong the QT interval.
Inform your doctor about any existing heart problems or medications you are taking. Close monitoring might be required, including ECGs, if you have risk factors for QT prolongation.
Myasthenia Gravis
Azithromycin may worsen symptoms of myasthenia gravis, a neuromuscular disorder causing muscle weakness. Patients with this condition should discuss the risks and benefits with their doctor before taking azithromycin.
Drug Interactions
Azithromycin interacts with several medications. Specifically, avoid concurrent use with drugs metabolized by the liver’s CYP3A4 enzyme system, such as certain statins, ergot alkaloids, or pimozide. Always provide your doctor with a complete list of medications you’re taking.
Pregnancy and Breastfeeding
While generally considered safe, the use of azithromycin during pregnancy or while breastfeeding requires careful consideration and should be discussed with your doctor to weigh the potential benefits against any potential risks.
